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FSC Biology: Genetics, questions with answers

Practise 42 real Federal Board questions on Genetics from 2023 to 2026. See the answer and explanation as soon as you answer.

42real questions
14multiple choice
5exam sessions

About Genetics in FSC Biology

Genetics is one of the 15 main chapters in our Federal Board FSC Biology question bank (11th and 12th class), and about 8% of its real questions come from it. Tayyari Karo has 42 real questions on this chapter from 2023 to 2026; 14 are multiple choice and marked instantly, and the rest are short and long questions with a model answer. By difficulty: 37 medium, 4 easy, 1 hard.

Work through the questions below, then open the explanation for each one. Redo the ones you missed a few days later.

Try 8 real questions

These are real past-paper questions. Think of your answer first, then open the explanation.

2026 Annual · 11th · Genetics

Polygenic inheritance results in:

  1. Single trait expression
  2. Continuous variation
  3. Dominant traits only
  4. Mutation only
Show answer and explanation

Answer: B. Continuous variation

When multiple genes act additively on one trait (polygenic inheritance), the phenotype shows continuous variation (e.g. height, skin colour) rather than discrete classes.

2026 Annual · 12th · Genetics

Range of the data 10, 12, 15, 11, 13, is:

  1. 15
  2. 2.5
  3. 5
  4. 10
Show answer and explanation

Answer: C. 5

Range = maximum − minimum = 15 − 10 = 5.

2025 1st Annual · 11th · Genetics

Identify the trait which is NOT controlled by polygenes:

  1. Intelligence
  2. Height
  3. Skin color
  4. Tongue rolling
Show answer and explanation

Answer: D. Tongue rolling

Tongue rolling is a simple Mendelian (single-gene) trait, whereas height, skin colour and intelligence are polygenic, showing continuous variation.

2025 1st Annual · 12th · Genetics

A couple has a child with cystic fibrosis: An autosomal disorder. If both parents are carrier and do not show symptoms, what is the probability that their next child will have cystic fibrosis?

  1. 25%
  2. 50%
  3. 75%
  4. 100%
Show answer and explanation

Answer: A. 25%

Cystic fibrosis is autosomal recessive; two carriers (Aa × Aa) give a 1/4 (25%) chance of an affected (aa) child.

2024 Annual · 12th · Genetics

Which of the following will be hemophilic?

  1. X^h X^H
  2. X^h Y
  3. X^H Y
  4. 2 and 3
Show answer and explanation

Answer: B. X^h Y

Since hemophilia is X-linked recessive, a male with genotype X^h Y is hemizygous for the defective allele and will be hemophilic; X^h X^H is an unaffected carrier female and X^H Y is a normal male.

2023 Annual · 12th · Genetics

A heterozygote red eyed female drosophila is mated with white eye male drosophila. What would be the expected %age of red eyed female as a result of cross?

  1. 25%
  2. 50%
  3. 75%
  4. 100%
Show answer and explanation

Answer: A. 25%

X^R X^r (red, heterozygous female) × X^r Y (white male) gives offspring in equal 1:1:1:1 proportions: X^R X^r (red female), X^r X^r (white female), X^R Y (red male), X^r Y (white male) — so red-eyed females make up 25% of total offspring.

2026 Annual · 11th · Genetics

Explain through a cross that incomplete dominance is a deviation from Mendel's law of segregation.

Show model answer

Mendel's law of segregation predicts that a cross between two heterozygotes (Rr × Rr) should give a 3:1 phenotypic ratio (dominant:recessive) because one allele completely dominates the other. In incomplete dominance, e.g. crossing red-flowered (RR) and white-flowered (rr) four o'clock plants, the F1 heterozygote (Rr) shows an intermediate pink phenotype instead of pure red. …

The full model answer is in the app.

2025 1st Annual · 12th · Genetics

Explain the XX-XY mechanism of sex determination in man. Why males are known to be heterogametic?

Show model answer

In humans, sex is determined by the sex chromosomes: females carry two X chromosomes (XX) and males carry one X and one Y chromosome (XY).
During meiosis, a female (XX) produces eggs that all carry a single X chromosome — she is homogametic (produces only one type of gamete). A male (XY) produces two types of sperm in equal numbers: half carry an X chromosome and half carry a Y chromosome — hence males are heterogametic (produce two different types of gametes with respect to sex chromosomes).
At fertilization, if an X-bearing sperm fertilizes the egg, the zygote is XX and develops as a female; if a Y-bearing sperm fertilizes the egg, the zygote is XY and develops as a male. …

The full model answer is in the app.

Sessions with Genetics questions

SessionQuestions
2026 Annual6
2025 1st Annual12
2025 2nd Annual11
2024 Annual8
2023 Annual5

Common questions

What does the Genetics chapter cover on this page?

42 real Federal Board (FBISE) Biology questions on Genetics from 2023 to 2026, for 11th and 12th class. Each one shows the session it came from.

Are the answers official?

No. We could not find an official FBISE marking scheme for these papers, so the answers and explanations are written by Tayyari Karo for practice. Check anything important with your teacher or textbook.

Is it free?

You can start free with no signup. A small set of papers per subject is free, and Premium unlocks the full question bank.

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