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O Level Biology: Gas exchange and respiration, questions with answers

Practise 43 real questions on Gas exchange and respiration from 2021 to 2026. See the answer and explanation as soon as you answer.

43real questions
28multiple choice
11exam sessions

About Gas exchange and respiration in O Level Biology

Gas exchange and respiration is one of the 13 main topics in our O Level Biology (Cambridge (CAIE) 5090) question bank, and about 7% of its real questions come from it. Tayyari Karo has 43 real questions on this topic from 2021 to 2026, from Paper 1, Paper 2, Paper 3, Paper 4; 28 are multiple choice and marked instantly, and the rest are structured questions with a model answer. By difficulty: 30 medium, 7 hard, 6 easy.

Work through the questions below, then open the explanation for each one. Redo the ones you missed a few days later.

Try 8 real questions

These are real past-paper questions. Think of your answer first, then open the explanation.

May/June 2026 · Paper 1 · Gas exchange and respiration

Which equation shows the type of respiration that can cause an 'oxygen debt' in muscles during vigorous exercise?

  1. glucose + oxygen -> carbon dioxide + water
  2. glucose -> lactic acid + carbon dioxide + water
  3. glucose -> ethanol + carbon dioxide
  4. glucose -> lactic acid
Show answer and explanation

Answer: D. glucose -> lactic acid

Anaerobic respiration in muscle produces lactic acid, which needs oxygen to remove afterwards (oxygen debt).

Oct/Nov 2025 · Paper 1 · Gas exchange and respiration

Which sets of muscles contract to cause the body to breathe in?

  1. diaphragm and external intercostal muscles
  2. diaphragm and internal intercostal muscles
  3. diaphragm muscles only
  4. external and internal intercostal muscles
Show answer and explanation

Answer: A. diaphragm and external intercostal muscles

May/June 2024 · Paper 1 · Gas exchange and respiration

Which equation represents anaerobic respiration in humans?

  1. glucose + carbon dioxide → lactic acid
  2. glucose → alcohol + carbon dioxide
  3. glucose → lactic acid
  4. glucose → lactic acid + carbon dioxide
Show answer and explanation

Answer: C. glucose → lactic acid

Human anaerobic respiration: glucose → lactic acid.

May/June 2023 · Paper 1 · Gas exchange and respiration

Which equation shows the type of respiration that can cause an 'oxygen debt' in muscles during vigorous exercise?

  1. glucose + oxygen → carbon dioxide + water
  2. glucose → lactic acid
  3. glucose → ethanol + carbon dioxide
  4. glucose → lactic acid + carbon dioxide + water
Show answer and explanation

Answer: B. glucose → lactic acid

Anaerobic respiration in muscles produces lactic acid, causing oxygen debt.

Oct/Nov 2022 · Paper 1 · Gas exchange and respiration

An experiment is set up with limewater in test-tubes 1 and 2; air is pumped through, passing a solution that absorbs carbon dioxide, then living animals. What is the appearance of the limewater in test-tubes 1 and 2 after 10 minutes?

  1. clear / clear
  2. clear / cloudy
  3. cloudy / clear
  4. cloudy / cloudy
Show answer and explanation

Answer: B. clear / cloudy

May/June 2021 · Paper 1 · Gas exchange and respiration

In an investigation, scientists treated plant roots with a chemical that stops aerobic respiration. They observed that after the treatment the plant roots absorbed nitrate ions more slowly. Which statement explains this observation?

  1. Anaerobic respiration does not release energy.
  2. The plant cells cannot respire.
  3. There is less energy for active transport of nitrate ions.
  4. There is less energy for diffusion of nitrate ions.
Show answer and explanation

Answer: C. There is less energy for active transport of nitrate ions.

Oct/Nov 2023 · Paper 2 · Gas exchange and respiration

A root hair cell respires aerobically. (a)(i) Name the structures within the cell that carry out aerobic respiration. [1] (a)(ii) Write the balanced symbol equation for aerobic respiration of glucose. [2] (b) State a weather condition that may lead to a root hair cell respiring anaerobically and explain. [2]

Show model answer

(a)(i) Mitochondria. (a)(ii) C6H12O6 + 6O2 -> 6CO2 + 6H2O. (b) Waterlogging (heavy rain) - reduces oxygen in soil so roots respire anaerobically (producing ethanol/lactic acid). Low humidity/high temperature increases transpiration/water loss also affecting.

Model answers; verify with 5090_w23_ms_21.

Oct/Nov 2022 · Paper 2 · Gas exchange and respiration

The forelimb of a lion has the same basic structure as the human arm (bones X, Y, ulna). (a) State the name of bone X and the muscle between bones X and Y. [2] (b)(i) Name the process used to release energy in the muscles when the lion starts to run. [1] (b)(ii) Explain why the lion can only run at maximum speed for a short time. [2]

Show model answer

(a) Bone X = humerus; muscle between X and Y = biceps (or triceps). (b)(i) Respiration (aerobic and then anaerobic). (b)(ii) Anaerobic respiration builds up lactic acid and oxygen debt; muscles tire, so it can only sustain max speed briefly before needing recovery.

Model answers; verify with 5090_w22_ms_21.

Sessions with Gas exchange and respiration questions

SessionPaper 1Paper 2Paper 3Paper 4
May/June 202612––
May/June 20252–––
Oct/Nov 20253–11
May/June 202421–1
Oct/Nov 20241–22
May/June 20233–––
Oct/Nov 202331––
May/June 202241––
Oct/Nov 202231––
May/June 202131––
Oct/Nov 202131––

Common questions

What does the Gas exchange and respiration topic cover on this page?

43 real O Level Biology (5090) questions on Gas exchange and respiration from 2021 to 2026, from Paper 1, Paper 2, Paper 3, Paper 4. Each one shows the year, session and paper it came from.

Do I get the answers and explanations?

Yes. Every question shows the correct answer and a short explanation the moment you answer.

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You can start free with no signup. A small set of papers per subject is free, and Premium unlocks every paper, the full question bank and the paper PDFs.

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