About Gas exchange and respiration in O Level Biology
Gas exchange and respiration is one of the 13 main topics in our O Level Biology (Cambridge (CAIE) 5090) question bank, and about 7% of its real questions come from it. Tayyari Karo has 43 real questions on this topic from 2021 to 2026, from Paper 1, Paper 2, Paper 3, Paper 4; 28 are multiple choice and marked instantly, and the rest are structured questions with a model answer. By difficulty: 30 medium, 7 hard, 6 easy.
Work through the questions below, then open the explanation for each one. Redo the ones you missed a few days later.
Try 8 real questions
These are real past-paper questions. Think of your answer first, then open the explanation.
May/June 2026 · Paper 1 · Gas exchange and respiration
Which equation shows the type of respiration that can cause an 'oxygen debt' in muscles during vigorous exercise?
- glucose + oxygen -> carbon dioxide + water
- glucose -> lactic acid + carbon dioxide + water
- glucose -> ethanol + carbon dioxide
- glucose -> lactic acid
Show answer and explanation
Answer: D. glucose -> lactic acid
Anaerobic respiration in muscle produces lactic acid, which needs oxygen to remove afterwards (oxygen debt).
Oct/Nov 2025 · Paper 1 · Gas exchange and respiration
Which sets of muscles contract to cause the body to breathe in?
- diaphragm and external intercostal muscles
- diaphragm and internal intercostal muscles
- diaphragm muscles only
- external and internal intercostal muscles
Show answer and explanation
Answer: A. diaphragm and external intercostal muscles
May/June 2024 · Paper 1 · Gas exchange and respiration
Which equation represents anaerobic respiration in humans?
- glucose + carbon dioxide → lactic acid
- glucose → alcohol + carbon dioxide
- glucose → lactic acid
- glucose → lactic acid + carbon dioxide
Show answer and explanation
Answer: C. glucose → lactic acid
Human anaerobic respiration: glucose → lactic acid.
May/June 2023 · Paper 1 · Gas exchange and respiration
Which equation shows the type of respiration that can cause an 'oxygen debt' in muscles during vigorous exercise?
- glucose + oxygen → carbon dioxide + water
- glucose → lactic acid
- glucose → ethanol + carbon dioxide
- glucose → lactic acid + carbon dioxide + water
Show answer and explanation
Answer: B. glucose → lactic acid
Anaerobic respiration in muscles produces lactic acid, causing oxygen debt.
Oct/Nov 2022 · Paper 1 · Gas exchange and respiration
An experiment is set up with limewater in test-tubes 1 and 2; air is pumped through, passing a solution that absorbs carbon dioxide, then living animals. What is the appearance of the limewater in test-tubes 1 and 2 after 10 minutes?
- clear / clear
- clear / cloudy
- cloudy / clear
- cloudy / cloudy
Show answer and explanation
Answer: B. clear / cloudy
May/June 2021 · Paper 1 · Gas exchange and respiration
In an investigation, scientists treated plant roots with a chemical that stops aerobic respiration. They observed that after the treatment the plant roots absorbed nitrate ions more slowly. Which statement explains this observation?
- Anaerobic respiration does not release energy.
- The plant cells cannot respire.
- There is less energy for active transport of nitrate ions.
- There is less energy for diffusion of nitrate ions.
Show answer and explanation
Answer: C. There is less energy for active transport of nitrate ions.
Oct/Nov 2023 · Paper 2 · Gas exchange and respiration
A root hair cell respires aerobically. (a)(i) Name the structures within the cell that carry out aerobic respiration. [1] (a)(ii) Write the balanced symbol equation for aerobic respiration of glucose. [2] (b) State a weather condition that may lead to a root hair cell respiring anaerobically and explain. [2]
Show model answer
(a)(i) Mitochondria. (a)(ii) C6H12O6 + 6O2 -> 6CO2 + 6H2O. (b) Waterlogging (heavy rain) - reduces oxygen in soil so roots respire anaerobically (producing ethanol/lactic acid). Low humidity/high temperature increases transpiration/water loss also affecting.
Model answers; verify with 5090_w23_ms_21.
Oct/Nov 2022 · Paper 2 · Gas exchange and respiration
The forelimb of a lion has the same basic structure as the human arm (bones X, Y, ulna). (a) State the name of bone X and the muscle between bones X and Y. [2] (b)(i) Name the process used to release energy in the muscles when the lion starts to run. [1] (b)(ii) Explain why the lion can only run at maximum speed for a short time. [2]
Show model answer
(a) Bone X = humerus; muscle between X and Y = biceps (or triceps). (b)(i) Respiration (aerobic and then anaerobic). (b)(ii) Anaerobic respiration builds up lactic acid and oxygen debt; muscles tire, so it can only sustain max speed briefly before needing recovery.
Model answers; verify with 5090_w22_ms_21.