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O Level Biology: Inheritance, variation and evolution, questions with answers

Practise 40 real questions on Inheritance, variation and evolution from 2021 to 2026. See the answer and explanation as soon as you answer.

40real questions
36multiple choice
11exam sessions

About Inheritance, variation and evolution in O Level Biology

Inheritance, variation and evolution is one of the 13 main topics in our O Level Biology (Cambridge (CAIE) 5090) question bank, and about 7% of its real questions come from it. Tayyari Karo has 40 real questions on this topic from 2021 to 2026, from Paper 1, Paper 2; 36 are multiple choice and marked instantly, and the rest are structured questions with a model answer. By difficulty: 33 medium, 6 easy, 1 hard.

Work through the questions below, then open the explanation for each one. Redo the ones you missed a few days later.

Try 7 real questions

These are real past-paper questions. Think of your answer first, then open the explanation.

May/June 2026 · Paper 1 · Inheritance, variation and evolution

What is an example of continuous variation?

  1. ABO blood groups
  2. body mass
  3. seed colour in peas
  4. seed shape in peas
Show answer and explanation

Answer: B. body mass

Body mass shows a range of values between extremes; the others fall into distinct categories.

Oct/Nov 2025 · Paper 1 · Inheritance, variation and evolution

Which statements refer to discontinuous variation (1 body mass 2 limited forms no intermediates 3 any value min to max 4 unaffected by environment 5 caused by genes only)?

  1. 1, 3 and 5
  2. 1 and 3 only
  3. 2, 4 and 5
  4. 2 and 4 only
Show answer and explanation

Answer: C. 2, 4 and 5

Oct/Nov 2024 · Paper 1 · Inheritance, variation and evolution

Night-blindness is inherited. Couple 4 and 5 are expecting their second child (individual 7). What is the probability that individual 7 will be a male and also show night-blindness?

  1. 0.500
  2. 0.300
  3. 0.250
  4. 0.125
Show answer and explanation

Answer: D. 0.125

Oct/Nov 2023 · Paper 1 · Inheritance, variation and evolution

A scientist takes four pairs of samples from a wild cherry tree. In which pair of samples could there be cells with different genotypes?

  1. two seeds
  2. two leaves
  3. two petals
  4. two root cuttings
Show answer and explanation

Answer: A. two seeds

Oct/Nov 2022 · Paper 1 · Inheritance, variation and evolution

A variety of snail has: StSt thick shells, StSn thin shells, SnSn do not survive. Two heterozygous snails are mated. What is the probability that a surviving snail of the next generation is a heterozygote?

  1. 0.00
  2. 0.25
  3. 0.50
  4. 0.67
Show answer and explanation

Answer: D. 0.67

May/June 2021 · Paper 1 · Inheritance, variation and evolution

Which statements about natural selection are correct? natural selection can lead to better adapted species surviving / natural selection can lead to extinction of a species / natural selection can lead to gene mutations occurring

  1. true / true / true
  2. true / true / false
  3. true / false / true
  4. false / true / true
Show answer and explanation

Answer: B. true / true / false

Oct/Nov 2021 · Paper 2 · Inheritance, variation and evolution

(a) Explain the role of the nucleus and cell division in the inheritance of characteristics from parents to offspring. [6] (b) Suggest how exposure to ionising radiation may affect inheritance of characteristics. [4]

Show model answer

(a) The nucleus contains chromosomes made of DNA; genes on the chromosomes carry instructions for characteristics; gametes are formed by meiosis and contain half the chromosome number; fertilisation joins male and female gametes so the offspring receives genes from both parents; mitosis divides cells for growth/repair, copying the genetic information. (b) Ionising radiation can cause mutations in DNA/gametes; these changes may be inherited by offspring; they can produce new alleles or harmful defects; increased mutation rate.

Best-effort; mark scheme not parsed.

Sessions with Inheritance, variation and evolution questions

SessionPaper 1Paper 2
May/June 20263–
May/June 202511
Oct/Nov 20254–
May/June 20245–
Oct/Nov 20244–
May/June 20233–
Oct/Nov 202331
May/June 20222–
Oct/Nov 202241
May/June 20213–
Oct/Nov 202141

Common questions

What does the Inheritance, variation and evolution topic cover on this page?

40 real O Level Biology (5090) questions on Inheritance, variation and evolution from 2021 to 2026, from Paper 1, Paper 2. Each one shows the year, session and paper it came from.

Do I get the answers and explanations?

Yes. Every question shows the correct answer and a short explanation the moment you answer.

Is it free?

You can start free with no signup. A small set of papers per subject is free, and Premium unlocks every paper, the full question bank and the paper PDFs.

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